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Feasibility and antitumor efficacy in vivo, of simultaneously targeting glycolysis, glutaminolysis and fatty acid synthesis using lonidamine, 6‑ diazo‑5‑oxo‑L‑norleucine and orlistat in colon cancer
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Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis | Journal of Virology
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Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo -L-Norleucine. - Abstract - Europe PMC
N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo- 5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders | Journal of Medicinal Chemistry
Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes | PLOS Biology
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WO2016112386A1 - Methods for bioanalysis of 6-diazo-5-oxo-l-norleucine (don) and other glutamine antagonists - Google Patents
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The combination of orlistat, lonidamine and 6‑diazo‑5‑oxo‑L‑norleucine induces a quiescent energetic phenotype and limits substrate flexibility in colon cancer cells
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Model studies towards prodrugs of the glutamine antagonist 6-diazo-5-oxo-l- norleucine (DON) containing a diazo precursor - ScienceDirect
Tumor-Targeted Delivery of 6-Diazo-5-oxo-l-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs | Journal of Medicinal Chemistry
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WO2016112386A1 - Methods for bioanalysis of 6-diazo-5-oxo-l-norleucine (don) and other glutamine antagonists - Google Patents
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Tumor-Targeted Delivery of 6-Diazo-5-oxo-l-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs | Journal of Medicinal Chemistry
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